Survodutide
Key Information:
Formula: C₁₉₂H₂₈₉N₄₇O₆₁
Molar Mass: ~4231.62 g/mol (or 4231.7)
Type: Synthetic peptide glucagon analog.
Function: Dual GLP-1/GCGR agonist for weight management and metabolic health.
How it Works
Dual Action:
It activates both glucagon and GLP-1 receptors, which helps control metabolism, energy expenditure, and fat reduction in the liver, offering benefits beyond single-receptor agonists like semaglutide.
Mechanism:
It mimics natural hormones to increase energy expenditure, decrease appetite, and directly reduce liver fat, making it effective for obesity and MASH.
Key Benefits & Findings
Weight Loss:
In Phase 2 trials, it achieved substantial weight loss (up to 18.7%) in people with obesity.
MASH Treatment:
Shows promise in reducing liver fat and fibrosis, even in patients with cirrhosis, a group often excluded from trials.
Cardiometabolic Health:
Also shows improvements in blood pressure and other obesity-related complications.
Comes in a box of 10 × 10mg
Survodutide
Key Information:
Formula: C₁₉₂H₂₈₉N₄₇O₆₁
Molar Mass: ~4231.62 g/mol (or 4231.7)
Type: Synthetic peptide glucagon analog.
Function: Dual GLP-1/GCGR agonist for weight management and metabolic health.
How it Works
Dual Action:
It activates both glucagon and GLP-1 receptors, which helps control metabolism, energy expenditure, and fat reduction in the liver, offering benefits beyond single-receptor agonists like semaglutide.
Mechanism:
It mimics natural hormones to increase energy expenditure, decrease appetite, and directly reduce liver fat, making it effective for obesity and MASH.
Key Benefits & Findings
Weight Loss:
In Phase 2 trials, it achieved substantial weight loss (up to 18.7%) in people with obesity.
MASH Treatment:
Shows promise in reducing liver fat and fibrosis, even in patients with cirrhosis, a group often excluded from trials.
Cardiometabolic Health:
Also shows improvements in blood pressure and other obesity-related complications.
Comes in a box of 10 × 10mg
Note:
For laboratory research use only.
Not intended for human consumption or therapeutic use.
Handling by trained research professionals is required.
